Academic radiology · 2022
Intermuscular Fat, But Not Subcutaneous Fat, Correlated With Major Complications After Primary Total Hip Arthroplasty.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Yu Jinlong, Wang Mingliang, Shen Hao
Аннотация
RATIONALE AND OBJECTIVES: To investigate the relationship between upper-thigh intermuscular fat, subcutaneous fat measured by CT and major complications after primary total hip arthroplasty (THA).
MATERIALS AND METHODS: Between 2015 and 2021, consecutive patients who had primary THA and preoperative hip CT were retrospectively included. Upper-thigh muscle cross-sectional intermuscular fat, subcutaneous fat, and muscle area were measured on hip CT images. The major complications included dislocation, aseptic loosening, infection, and periprosthetic fracture. The effect of upper-thigh intermuscular fat, subcutaneous fat and muscle area on the outcome was analyzed using multivariable cox proportional hazards analysis. Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated.
RESULTS: A total of 3028 patients were included and 71 (2.34%) of them had major complications. During a median of 25 months of follow-up, patients showed increased incidence of total major complications with increased intermuscular fat area (log-rank p = 0.012). The multivariable cox regression revealed that per SD increment in intermuscular fat area was associated with higher risk of total major complications (HR = 2.04, 95% CI = 1.71-2.43, p < 0.001), dislocation (HR = 1.96, 95% CI = 1.44-2.66, p < 0.001), aseptic loosening (HR = 2.02, 95% CI = 1.30-3.16, p = 0.002), infection (HR = 1.94, 95% CI = 1.24-3.05, p = 0.004), and periprosthetic fracture (HR = 2.26, 95% CI = 1.67-3.07, p < 0.001).
CONCLUSION: Upper-thigh intermuscular fat, but not subcutaneous fat measured on CT associated with the risk of major complications after primary THA.
MATERIALS AND METHODS: Between 2015 and 2021, consecutive patients who had primary THA and preoperative hip CT were retrospectively included. Upper-thigh muscle cross-sectional intermuscular fat, subcutaneous fat, and muscle area were measured on hip CT images. The major complications included dislocation, aseptic loosening, infection, and periprosthetic fracture. The effect of upper-thigh intermuscular fat, subcutaneous fat and muscle area on the outcome was analyzed using multivariable cox proportional hazards analysis. Adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated.
RESULTS: A total of 3028 patients were included and 71 (2.34%) of them had major complications. During a median of 25 months of follow-up, patients showed increased incidence of total major complications with increased intermuscular fat area (log-rank p = 0.012). The multivariable cox regression revealed that per SD increment in intermuscular fat area was associated with higher risk of total major complications (HR = 2.04, 95% CI = 1.71-2.43, p < 0.001), dislocation (HR = 1.96, 95% CI = 1.44-2.66, p < 0.001), aseptic loosening (HR = 2.02, 95% CI = 1.30-3.16, p = 0.002), infection (HR = 1.94, 95% CI = 1.24-3.05, p = 0.004), and periprosthetic fracture (HR = 2.26, 95% CI = 1.67-3.07, p < 0.001).
CONCLUSION: Upper-thigh intermuscular fat, but not subcutaneous fat measured on CT associated with the risk of major complications after primary THA.