The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2026
Prenatal radiofrequency ablation for bronchopulmonary sequestration: a case report of successful fetal intervention and longitudinal outcomes.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Xi Hui, Su Huilin, Jiang Zheming, Li GuiJun, Luo Yingchun, Tang Yabing, Zhang Huiping, Ling Dandan
Аннотация
INTRODUCTION: Bronchopulmonary sequestration (BPS), a rare congenital pulmonary malformation, is characterized by nonfunctional pulmonary parenchyma with aberrant systemic arterial supply (typically from the aorta or its major branches) and absence of communication with the tracheobronchial tree. Large BPS lesions pose significant fetal risks, including hydrops fetalis, mediastinal shift, and polyhydramnios, necessitating timely prenatal intervention to prevent fetal demise.
CASE PRESENTATION: We present a case of successful ultrasound-guided radiofrequency ablation (RFA) of the feeding artery in a fetus diagnosed with BPS at 22 weeks of gestation. Under ultrasound guidance, a 17-gauge RFA needle was percutaneously inserted into the aberrant feeding artery, achieving complete vascular occlusion without procedural complications. Serial prenatal ultrasounds demonstrated progressive lesion involution. The pregnancy was complicated by cephalopelvic disproportion (CPD), prompting cesarean delivery at 38 weeks. Neonatal computed tomography (CT) confirmed shrinkage of the residual sequestration tissue. Six-month postnatal follow-up revealed normal respiratory function, age-appropriate growth, and developmental milestones.
CONCLUSION: RFA represents a safe and effective minimally invasive prenatal therapy for BPS. Candidate selection requires comprehensive evaluation of fetal hydrops, lesion size, gestational age, and parental preferences. Amniotic fluid sampling during the procedure is advisable for genetic/ancillary testing. This case highlights the utility of RFA in optimizing fetal outcomes while avoiding open neonatal period surgery. Long-term neonatal follow-up supports the durability of vascular occlusion and functional recovery.
CASE PRESENTATION: We present a case of successful ultrasound-guided radiofrequency ablation (RFA) of the feeding artery in a fetus diagnosed with BPS at 22 weeks of gestation. Under ultrasound guidance, a 17-gauge RFA needle was percutaneously inserted into the aberrant feeding artery, achieving complete vascular occlusion without procedural complications. Serial prenatal ultrasounds demonstrated progressive lesion involution. The pregnancy was complicated by cephalopelvic disproportion (CPD), prompting cesarean delivery at 38 weeks. Neonatal computed tomography (CT) confirmed shrinkage of the residual sequestration tissue. Six-month postnatal follow-up revealed normal respiratory function, age-appropriate growth, and developmental milestones.
CONCLUSION: RFA represents a safe and effective minimally invasive prenatal therapy for BPS. Candidate selection requires comprehensive evaluation of fetal hydrops, lesion size, gestational age, and parental preferences. Amniotic fluid sampling during the procedure is advisable for genetic/ancillary testing. This case highlights the utility of RFA in optimizing fetal outcomes while avoiding open neonatal period surgery. Long-term neonatal follow-up supports the durability of vascular occlusion and functional recovery.