Novel Use of a Synthetic Electrospun Wound Matrix in an Extensive Forearm Degloving Injury: Case Report and Review of the Literature.

Wound matrices, such as synthetic electrospun fiber matrices (SEFMs), provide innovative scaffolds to allow for complex wound healing. This case report described a 74-year-old woman with an 80% degloving injury of the left forearm caused by a fall. Due to her medical history, including liver cirrhosis, malnutrition, and previous orthopedic injuries, traditional skin grafting was deemed too risky. Instead, following initial debridement and application of negative pressure wound therapy, an SEFM sheet was applied and later supplemented with 5 applications of particulate SEFM. In subsequent follow-up visits, granulation tissue and wound closure progressed. By postoperative day 96, the wound was mostly healed with minimal residual erythema and full restoration of functionality. This case highlights the efficacy of SEFM in managing extensive injuries, providing an alternative for large, complex wounds, especially for patients with significant comorbidities who are poor candidates for traditional skin grafting.