Nonsurgical management of primary ovarian pregnancy with transvaginal ultrasound-guided local administration of methotrexate.

Primary ovarian pregnancy is a rare form of ectopic gestation and one that is often diagnosed only at the time of surgery. We report the first case to our knowledge of a live primary ovarian pregnancy diagnosed by transvaginal ultrasonography and successfully treated with transvaginal-guided aspiration and injection of methotrexate. Primary ovarian pregnancy can be diagnosed early in gestation with transvaginal sonography, affording the opportunity to successfully be managed with local administration of methotrexate.