[Vascular complications and their effect on fetal-maternal outcome and therapeutic approach in diabetic women].

Metabolic disturbances related to glucose intolerance and hyperglycemia are known to affect the health and life of women planning the pregnancy. They also are capable of impairing the development of fetuses and newborns. Remarkable advances have been made in recent years in clarifying the metabolic processes that occur during pregnancy and their effect on intrauterine fetal development. Clinicians have become aware of the observations, that maternal diabetes and the occurrence of complications are related to the duration of the disease, to the grade of hyperglycemia and to the time of pregnancy when hyperglycemia occurred. Since the last decade, numerous epidemiological studies have confirmed that a good balanced diabetes mellitus in pregnant women leads to the fruitful fetal development and contributes to reducing maternal mortality. The aim of this study was to discuss the update guidelines for managing diabetic patients with vascular complications before and during the course of pregnancy.