Early human development · 2025
Exploring congenital hypertrophic pyloric stenosis in preterm and low weight infants: A Western China perspective.
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Hou Jinfeng, Cui Mengying, Wang Yi, Guo Zhenhua, Feng Wei, Liu Wei
Аннотация
PURPOSE: To retrospectively analyze the clinical characteristics of congenital hypertrophic pyloric stenosis (CHPS) patients with different gestational ages and admission weights.
MATERIALS AND METHODS: The clinical records of CHPS patients between 2008 and 2022 were retrospectively reviewed. The patients were classified into two main groups: premature group and full-term group. Moreover, they were further divided into two subgroups based on their admission weight, namely the ≤3 kg group and the >3 kg group.
RESULTS: The median age at the onset of the disease for premature infants was found to be later than that for full-term infants, with values of 29.00 days and 22.00 days respectively (P = 0.015). In terms of the proportion of patients with dehydration, it was significantly higher in the premature infants group compared to the full-term infants group, reaching 45.83 % and 25.30 % respectively (P = 0.026). Regarding the median pyloric muscle thickness, it was 0.45 (0.43-0.515) cm in the weight ≤3 kg group and 0.48 (0.43-0.53) cm in the weight >3 kg group, with a significant difference (P = 0.028).
CONCLUSION: There are distinct differences in the clinical characteristics of CHPS patients with different gestational ages at birth and admission weights. Premature infants show a later onset age and a higher proportion of dehydration. Additionally, the pyloric muscle thickness is also related to the admission weight of infants.
MATERIALS AND METHODS: The clinical records of CHPS patients between 2008 and 2022 were retrospectively reviewed. The patients were classified into two main groups: premature group and full-term group. Moreover, they were further divided into two subgroups based on their admission weight, namely the ≤3 kg group and the >3 kg group.
RESULTS: The median age at the onset of the disease for premature infants was found to be later than that for full-term infants, with values of 29.00 days and 22.00 days respectively (P = 0.015). In terms of the proportion of patients with dehydration, it was significantly higher in the premature infants group compared to the full-term infants group, reaching 45.83 % and 25.30 % respectively (P = 0.026). Regarding the median pyloric muscle thickness, it was 0.45 (0.43-0.515) cm in the weight ≤3 kg group and 0.48 (0.43-0.53) cm in the weight >3 kg group, with a significant difference (P = 0.028).
CONCLUSION: There are distinct differences in the clinical characteristics of CHPS patients with different gestational ages at birth and admission weights. Premature infants show a later onset age and a higher proportion of dehydration. Additionally, the pyloric muscle thickness is also related to the admission weight of infants.