Biomarkers in medicine · 2023
Evaluation of HSP70 levels in ectopic pregnancy, abortus imminens and intrauterine pregnancy.
СтатьяНазвание и аннотация: Перевод в очереди
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Yıldız Şükrü, Karakaş Sema, Kaya Cihan, Kural Alev, Gedikbaşı Asuman, Ekin Deniz, Serhanoğlu Zınar, Çaypınar Sema S, Ekin Murat
Аннотация
Aim: To assess the serum levels of HSP70 concentrations in ectopic pregnancy (EP) patients compared with abortus imminens (AI) patients and healthy controls. Materials & methods: Age-matched patients were divided into three groups, with 30 patients in each group: EP, AI and healthy intrauterine pregnancy groups. Blood samples were taken from the antecubital vein and kept for HSP70 analysis. Results: The HSP70 levels were higher in the EP group than in AI patients and healthy controls (p < 0.05). The area under the curve for the serum HSP70 assay reached a value of 0.81 for a cutoff point of 11.12 pg/ml, which identified women with EP. Conclusion: Serum HSP70 levels increased in women with EP compared with healthy controls and women with AI.