Successful Vaginal Delivery in a Pregnant Woman With Bernard-Soulier Syndrome: A Case Report.

Bernard-Soulier syndrome (BSS) is a rare inherited platelet disorder that poses major risks during pregnancy because of potential bleeding complications. Managing such cases in low-resource settings is especially challenging. We report the case of a 23-year-old Afghan woman with BSS who achieved a successful full-term vaginal delivery at a tertiary center. Early referral, coordinated management by hematology and obstetric teams, prophylactic platelet transfusions, and prompt treatment of postpartum hemorrhage led to a favorable maternal and neonatal outcome. This experience shows that, even where advanced laboratory and transfusion resources are limited, structured planning, timely communication, and preparedness can ensure a safe delivery for women with complex hematologic disorders.