Senna Laxative-Associated Severe Ischemic Bowel Disease in an 87-Year-Old Patient: A Clinical Warning.

Senna laxative, one of the major stimulant laxatives, has received less attention regarding its potential risk of intestinal ischemia in the elderly population. An 87-year-old female with a past medical history of chronic constipation developed abdominal pain and fever after oral ingestion of senna laxative for constipation and was subsequently diagnosed with ischemic bowel disease upon hospitalization. Symptomatic and supportive treatment, such as antibiotics, acid inhibition and stomach protection, fluid replenishment, and intravenous nutrition, was given. After treatment, the patient's condition stabilized, her symptoms improved, and she was allowed to leave the hospital. This case highlights that the use of senna laxative in elderly patients may lead to severe ischemic intestinal disease. Clinicians should be vigilant about the adverse reactions of senna laxative in elderly patients.