Canadian journal of ophthalmology. Journal canadien d'ophtalmologie · 2015
Sensitivity of multifocal electroretinography (mfERG) in detecting siderosis.
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Gupta Shikha, Midha Neha, Gogia Varun, Sahay Pranita, Pandey Veena, Venkatesh Pradeep
Аннотация
OBJECTIVE: To evaluate use of multifocal electroretinography (mfERG) in diagnosing retinal toxicity from siderosis with normal ERG.
DESIGN: Prospective case series.
PARTICIPANTS: Six patients with retained intraocular foreign body were recruited.
METHODS: The affected eye of the patients had no clinical evidence of siderosis, had similar full-field photopic 3.0 ERG compared with the fellow eye, and had subnormal visual acuity. Group averages in each MfERG ring for implicit time and amplitude at P1 wave were compared between affected and fellow eye to look for latent siderosis.
RESULTS: On mfERG, no statistical difference in group averaged amplitude was observed; however, a significant difference (p < 0.05) was found in group averaged latency between fellow and affected eye at most tested rings (<2 degree, 2-5 degree, and >15 degree rings). Average latency for overall retinal area mapped also showed significant difference (p = 0.010).
CONCLUSIONS: Increased mfERG latency may serve as an early predictor of retinal damage from siderosis when full-field ERG is normal.
DESIGN: Prospective case series.
PARTICIPANTS: Six patients with retained intraocular foreign body were recruited.
METHODS: The affected eye of the patients had no clinical evidence of siderosis, had similar full-field photopic 3.0 ERG compared with the fellow eye, and had subnormal visual acuity. Group averages in each MfERG ring for implicit time and amplitude at P1 wave were compared between affected and fellow eye to look for latent siderosis.
RESULTS: On mfERG, no statistical difference in group averaged amplitude was observed; however, a significant difference (p < 0.05) was found in group averaged latency between fellow and affected eye at most tested rings (<2 degree, 2-5 degree, and >15 degree rings). Average latency for overall retinal area mapped also showed significant difference (p = 0.010).
CONCLUSIONS: Increased mfERG latency may serve as an early predictor of retinal damage from siderosis when full-field ERG is normal.