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DOI 10.3389/fmed.2025.1653754

Медицинская библиотека · Frontiers in medicine · 2025

Dendritic fibromyxolipoma of the male breast: case report and literary review.

Li Xiaolan, Wu Demian, Tian Xiaoxue, Xu Ting, Ge Qiyao, Luo Shuai, Wang Jinjing

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Аннотация

BACKGROUND

Dendritic fibromyxolipoma (DFML) represents a benign lipomatous tumor. Its rarity and distinctive morphology can lead to misinterpretation of other mesenchymal malignancies, which may result in unnecessary aggressive treatments.

CASE PRESENTATION: A 39-year-old male presented with a left mammary mass that had been noticed 1 year earlier. Chest computed tomography identified a nodule characterized by fat density in the left mammary region. The initial clinical impression was gynecomastia. A local excision of the left mammary mass was subsequently performed. Histopathological analysis confirmed the diagnosis of DFML. Post-surgical follow-up over 38 months showed no recurrence.

CONCLUSION

DFML is a benign lipomatous tumor with unique morphological features. Complete surgical excision typically leads to no recurrence. This report documents the first known instance of DFML in the mammary gland of a male patient. Furthermore, an analysis of 95 previously documented cases of DFML was conducted. It is strongly advocated that the World Health Organization reclassify DFML as a mucinous subtype of spindle cell lipoma. This reclassification would improve the understanding of DFML and help avoid unnecessary aggressive treatments due to misdiagnosis as a malignancy.

Для цитирования: Li Xiaolan, Wu Demian, Tian Xiaoxue, Xu Ting, Ge Qiyao, Luo Shuai, Wang Jinjing. Dendritic fibromyxolipoma of the male breast: case report and literary review.. Frontiers in medicine. 2025. DOI: 10.3389/fmed.2025.1653754.
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