Acta paediatrica (Oslo, Norway : 1992) · 2025
Prone Positioning Was Associated With Less Hypoxemic Events and Improved Feeding Tolerance in Preterm Infants.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Bohnhorst Bettina, Lutz Eva, Pirr Sabine, Peter Corinna, Böhne Carolin
Аннотация
AIM: Cardiorespiratory events such as apnea, bradycardia and hypoxemia are common in preterm infants and may contribute to an impaired neurodevelopmental outcome. We hypothesised a significant reduction in the incidence of hypoxemia, bradycardia and gastric residuals in the prone position.
METHODS: In this monocentric, prospective, randomised, two-arm crossover trial, at a tertiary university hospital, 48 preterm infants with a gestational age of < 32 weeks and a postmenstrual age of < 34 weeks were randomised to either a prone-supine or a supine-prone sequence of cardiorespiratory monitoring over a period of 24 h. The primary outcome parameter was the cumulative frequency of hypoxemias and bradycardias; secondary parameters comprised evaluation of basal parameters, hypoxemias, bradycardias and the amount of gastric residuals.
RESULTS: The cumulative frequency of hypoxemias and bradycardias and the number of severe hypoxemias (peripheral oxygen saturation [SpO2] < 80%) were halved in the prone position (p = 0.03). Median basal SpO2 was significantly higher (p = 0.01) and gastric residuals were significantly lower (p = 0.0002) in the prone position. The frequency of apneas (> 10 s) was significantly increased in the prone position (p = 0.01).
CONCLUSION: Prone positioning of preterm infants significantly reduces the cumulative frequency of hypoxemias and bradycardias, severe hypoxemias and gastric residuals while increasing basal SpO2.
METHODS: In this monocentric, prospective, randomised, two-arm crossover trial, at a tertiary university hospital, 48 preterm infants with a gestational age of < 32 weeks and a postmenstrual age of < 34 weeks were randomised to either a prone-supine or a supine-prone sequence of cardiorespiratory monitoring over a period of 24 h. The primary outcome parameter was the cumulative frequency of hypoxemias and bradycardias; secondary parameters comprised evaluation of basal parameters, hypoxemias, bradycardias and the amount of gastric residuals.
RESULTS: The cumulative frequency of hypoxemias and bradycardias and the number of severe hypoxemias (peripheral oxygen saturation [SpO2] < 80%) were halved in the prone position (p = 0.03). Median basal SpO2 was significantly higher (p = 0.01) and gastric residuals were significantly lower (p = 0.0002) in the prone position. The frequency of apneas (> 10 s) was significantly increased in the prone position (p = 0.01).
CONCLUSION: Prone positioning of preterm infants significantly reduces the cumulative frequency of hypoxemias and bradycardias, severe hypoxemias and gastric residuals while increasing basal SpO2.