Amniotic membrane allograft for salvage of a complex abdominal wall defect following mesh explantation and wound dehiscence: a case report.

Postoperative abdominal wound dehiscence following mesh hernia repair presents a severe surgical challenge. In comorbid elderly patients, definitive abdominal wall reconstruction after mesh explantation carries prohibitive mortality risks. We present a 72-year-old homebound female with a chronic, dehisced midline abdominal wound (17.0 × 2.0 × 1.0 cm) following complicated hernia surgery and subsequent mesh removal at an outside facility. To minimize perioperative risks, a staged, non-reconstructive soft-tissue salvage approach was utilized. The patient underwent two serial operative debridements under monitored anesthesia care and two weeks of continuous negative pressure wound therapy at -125 mmHg. After achieving clean granulation bed over a structurally intact and closed deep fascia, a dehydrated human amniotic membrane allograft (AmnioAMP-MP) was applied. Complete wound closure was achieved within six weeks without secondary mesh reconstruction or complications. Amniotic allografts represent an effective salvage modality for complex abdominal soft-tissue wounds over intact fascial planes.