[Identification of additional diagnostic signs of gas-detonation wounds of the lower extremities in blast trauma using the immunohistochemistry method].

OBJECTIVE

To study pathohistological changes and evaluate the intensity of the immunohistochemical (IHC) reaction in soft tissues in explosive gas-detonation wounds of the lower extremities along the conditional zones within the topographic-anatomical levels of damage.

MATERIAL AND

METHODS

Biological material from 16 corpses of individuals (men aged 25-36 years) who died from explosive trauma with gas-detonation damage to the lower extremities was examined using forensic histology and ICG research methods.

RESULTS

The pathohistological picture of soft tissue damage to the lower extremities resulting from gas-detonation exposure during explosive trauma was clarified and supplemented; additional diagnostic signs (markers) of vitality and soft tissue reaction were identified over the conditional zones within the topographic and anatomical levels of damage using the IHC method.

CONCLUSION

The obtained data can be used in the practice of forensic medical examination in identifying and substantiating diagnostic signs of gas-detonation wounds of the lower extremities.