True osseous metaplasia of the endometrium: the bone is not from a fetus.

OBJECTIVE

To identify the origin of calcified tissue in endometrial ossification.

DESIGN

DNA analyses from the ossified tissue and from the woman were studied to compare both genotypes.

SETTING

University and general hospitals.

PATIENT(S): A 27-year-old infertile woman diagnosed of osseous metaplasia of the endometrium.

INTERVENTION(S): Hysteroscopic resection of the endometrial osseous metaplasia for DNA analysis.

MAIN OUTCOME MEASURE(S): DNA comparison between the patient and the osseous tissue extracted from the uterus.

RESULT(S): All markers produced the same allele length for both blood and endometrial biopsy (including bones), thus confirming the same genetic origin.

CONCLUSION(S): Endometrial ossification is derived from the patient, resulting in a true osseous metaplasia.