Coexistence of Cornual Pregnancy and Placenta Increta: A Report of a Rare Case.

Placenta accreta spectrum (PAS) comprises abnormal placental adherence to the uterine wall, typically associated with prior cesarean or other uterine surgery. Cornual pregnancies are a rare form of ectopic gestation, associated with a high risk of uterine rupture. We describe the case of a 37-year-old woman with no prior uterine surgeries, who was diagnosed with a cornual pregnancy associated with placenta increta. Ultrasound findings included fetal malformations and signs of placental invasion. After fetal demise and termination, surgical exploration revealed a uterine rupture at the right cornua. The histopathological examination confirmed a cornual pregnancy with placenta increta. This case underscores the importance of maintaining a high index of suspicion for PAS in atypical clinical contexts, particularly when coexisting with cornual pregnancy, due to the elevated risk of uterine rupture.