Predicting steroid treatment benefit in IgA nephropathy: are we ready for precision care?

The treatment of patients with IgA nephropathy at risk of disease progression often requires therapies addressing the underlying immunologic pathogenesis. To date, steroids remain a viable treatment option; however, their use should be balanced against known associated toxicity. Canney et al. developed a prediction tool that utilizes readily available clinical data to calculate the expected response to steroid therapy for an individual patient. This shift to data-informed, patient-specific decision is the essence of personalized care.