Irish journal of medical science · 2026
A retrospective case series of primary spinal tumours at the national spinal injuries unit.
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Flaherty Ella, Deane Emelia, McDonnell Jake, Ó Conaill Tiarnán, O'Malley Sandra, O'Neill Cathleen, Cunnife Grainne, Butler Joseph, Morris Seamus, Darwish Stacey
Аннотация
BACKGROUND: Primary extradural tumours of the spine are a rare group of spinal tumours. Current literature reporting demographic variables and prognostic information is limited. No prior Irish database has comprehensively compiled this data.
AIMS: To create the first database in Ireland reporting the demographics and outcome information of extradural spinal tumours in Ireland.
METHODS: Retrospective case series analysing population-based data from the National Spinal Injuries Unit from 1992-2021. ICD-10 codes C41.2 and C41.4 were used to extract data from the Mater Misericordiae University Hospital databases, reporting demographics, treatment, and survival outcomes.
RESULTS: 31 extradural spinal tumours were identified. Chondrosarcomas were the most common tumour subtype (26%), with chordomas and giant cell tumours both the second most common subtypes (16%). The thoracic spine was the predominant location (51.6%). The mean patient age was 44.4 years, with a male predominance (65%). Surgical excision was performed in all cases, with a complication rate of 74.2% and a recurrence of 48.4%. Cervical tumours had significantly higher recurrence (100%) than non-cervical (40.7%, p = 0.043). Overall mortality was 22.6%, with 5-year survival highest for cervical and sacral tumours (100%) and lowest for lumbar (66.7%) and thoracic tumours (72.2%).
CONCLUSION: Primary extradural spinal tumours are rare tumours but impose a significant healthcare burden, as evidenced by prolonged hospital stays and complication rates. Management requires a multidisciplinary approach in a specialist centre. The underutilisation and variability of adjuvant therapies in this cohort underscores the need for further research and development of standardised multimodal treatment protocols.
AIMS: To create the first database in Ireland reporting the demographics and outcome information of extradural spinal tumours in Ireland.
METHODS: Retrospective case series analysing population-based data from the National Spinal Injuries Unit from 1992-2021. ICD-10 codes C41.2 and C41.4 were used to extract data from the Mater Misericordiae University Hospital databases, reporting demographics, treatment, and survival outcomes.
RESULTS: 31 extradural spinal tumours were identified. Chondrosarcomas were the most common tumour subtype (26%), with chordomas and giant cell tumours both the second most common subtypes (16%). The thoracic spine was the predominant location (51.6%). The mean patient age was 44.4 years, with a male predominance (65%). Surgical excision was performed in all cases, with a complication rate of 74.2% and a recurrence of 48.4%. Cervical tumours had significantly higher recurrence (100%) than non-cervical (40.7%, p = 0.043). Overall mortality was 22.6%, with 5-year survival highest for cervical and sacral tumours (100%) and lowest for lumbar (66.7%) and thoracic tumours (72.2%).
CONCLUSION: Primary extradural spinal tumours are rare tumours but impose a significant healthcare burden, as evidenced by prolonged hospital stays and complication rates. Management requires a multidisciplinary approach in a specialist centre. The underutilisation and variability of adjuvant therapies in this cohort underscores the need for further research and development of standardised multimodal treatment protocols.