Heart rhythm · 2026
Feasibility and safety of ablation using a dual-energy, lattice-tip, map-and-ablate catheter in patients with mechanical heart valves.
СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ошибки и ограничения
История · было → стало
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Keller Jonas, Krisai Philipp, Küffer Thomas, Herrera-Siklody Claudia, Tanner Hildegard, Kozhuharov Nikola, Spahiu Valon, Knecht Sven, Sticherling Christian, Kovacs Boldizsar, Reichlin Tobias, Roten Laurent
Аннотация
BACKGROUND: Catheter ablation near mechanical prosthetic valves is associated with a risk of catheter-valve interaction and entrapment.
OBJECTIVE: This study aimed to evaluate the feasibility, safety, and efficacy of atrial ablation using a dual-energy, lattice-tip catheter in patients with mechanical heart valves.
METHODS: Consecutive patients undergoing atrial catheter ablation near a mechanical valve using the Sphere-9 catheter were identified at 2 tertiary centers. Primary safety endpoints included abortion of ablation because of catheter interference and procedural complications. Freedom from atrial tachyarrhythmia during follow-up was assessed as an efficacy endpoint. An in vitro valve interaction testing was additionally performed.
RESULTS: 9 patients (median age 59 years; 56% male) were identified. Ablation lines anchored to a mechanical valve were created in 6 patients, using radiofrequency ablation close to the valve in 5 patients and pulsed-field ablation in 1 patient. Interference during ablation leading to abortion of individual applications occurred in 3 patients, all during radiofrequency ablation, without preventing completion of the intended ablation strategy. No catheter entrapment, valve dysfunction, or procedural adverse events occurred. After a median follow-up of 114 days, all patients were free from recurrent atrial tachyarrhythmias. Bench testing demonstrated no propensity of the lattice-tip catheter to become wedged within a bileaflet mechanical heart valve.
CONCLUSION: Atrial ablation using a lattice-tip catheter seems feasible in patients with mechanical heart valves. No catheter entrapment or major complications were observed. However, given the small sample size, these findings should be interpreted as preliminary, and larger studies are needed to better assess safety and clinical outcomes.
OBJECTIVE: This study aimed to evaluate the feasibility, safety, and efficacy of atrial ablation using a dual-energy, lattice-tip catheter in patients with mechanical heart valves.
METHODS: Consecutive patients undergoing atrial catheter ablation near a mechanical valve using the Sphere-9 catheter were identified at 2 tertiary centers. Primary safety endpoints included abortion of ablation because of catheter interference and procedural complications. Freedom from atrial tachyarrhythmia during follow-up was assessed as an efficacy endpoint. An in vitro valve interaction testing was additionally performed.
RESULTS: 9 patients (median age 59 years; 56% male) were identified. Ablation lines anchored to a mechanical valve were created in 6 patients, using radiofrequency ablation close to the valve in 5 patients and pulsed-field ablation in 1 patient. Interference during ablation leading to abortion of individual applications occurred in 3 patients, all during radiofrequency ablation, without preventing completion of the intended ablation strategy. No catheter entrapment, valve dysfunction, or procedural adverse events occurred. After a median follow-up of 114 days, all patients were free from recurrent atrial tachyarrhythmias. Bench testing demonstrated no propensity of the lattice-tip catheter to become wedged within a bileaflet mechanical heart valve.
CONCLUSION: Atrial ablation using a lattice-tip catheter seems feasible in patients with mechanical heart valves. No catheter entrapment or major complications were observed. However, given the small sample size, these findings should be interpreted as preliminary, and larger studies are needed to better assess safety and clinical outcomes.