Archives de pediatrie : organe officiel de la Societe francaise de pediatrie · 2026
Moving from surgical to transcatheter patent ductus arteriosus closure in infants weighing 2 to 6 kilos: A monocentric experience.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Gloanec Marine, Quennelle Sophie, Louali Fedoua El, Gran Célia, Lenoir Marien, Aldebert Philippe, Paoli Florent, Fouilloux Virginie, Ovaert Caroline
Аннотация
INTRODUCTION: Transcatheter closure of patent ductus arteriosus (PDA) is expanding due to the fast development of new techniques and new materials. Miniaturization of devices currently allows transcatheter closure of ducts in very small patients. Few published data are however available in the 2 to 6 kilograms population.
OBJECTIVE: This study aims to describe and evaluate recent practices and experience in a medium-sized tertiary referral centre.
METHODS: We conducted a retrospective observational study comparing percutaneous and surgical duct closure in children weighing between 2 and 6 kilograms at the University Hospital of La Timone, Marseille, France. We analyzed clinical, procedural, and follow-up data, especially success rate of the percutaneous closure and complications related to the procedures. Additionally, the duration of mechanical ventilation, and of hospital stays of each procedure were compared.
RESULTS: Between 2014 and 2021, 31 patients weighing 2 to 6 kilos, were referred for transcatheter PDA closure and 22 patients for surgical closure of the PDA. Median age was respectively 5.1 [2.9-6.3] and 2.4 [2-3.2] months. Median weight 4660 [3950-5450] versus 3184 [2287-3775] grams. The success rate was 77.42 % (n = 24/31) for the transcatheter group versus 100 % for the surgical group. No patient died or experienced major adverse event because of the procedure. Minor adverse events occurred in 6/24 patients of the transcatheter group and 2/22 patients of the surgical group. The duration of mechanical ventilation was significantly shorter in the percutaneous group. The length of hospital stay was significantly shorter in the transcatheter group with a median of 2 [2.00-4.00] days compared to 8.5 [5.25-15.50] days in the surgical group (p < 0.001).
CONCLUSION: In our experience, percutaneous closure of patent ductus arteriosus is an efficient and safe alternative to surgery in 2 to 6 kg patients. Larger, multicentre studies are needed to confirm this statement.
OBJECTIVE: This study aims to describe and evaluate recent practices and experience in a medium-sized tertiary referral centre.
METHODS: We conducted a retrospective observational study comparing percutaneous and surgical duct closure in children weighing between 2 and 6 kilograms at the University Hospital of La Timone, Marseille, France. We analyzed clinical, procedural, and follow-up data, especially success rate of the percutaneous closure and complications related to the procedures. Additionally, the duration of mechanical ventilation, and of hospital stays of each procedure were compared.
RESULTS: Between 2014 and 2021, 31 patients weighing 2 to 6 kilos, were referred for transcatheter PDA closure and 22 patients for surgical closure of the PDA. Median age was respectively 5.1 [2.9-6.3] and 2.4 [2-3.2] months. Median weight 4660 [3950-5450] versus 3184 [2287-3775] grams. The success rate was 77.42 % (n = 24/31) for the transcatheter group versus 100 % for the surgical group. No patient died or experienced major adverse event because of the procedure. Minor adverse events occurred in 6/24 patients of the transcatheter group and 2/22 patients of the surgical group. The duration of mechanical ventilation was significantly shorter in the percutaneous group. The length of hospital stay was significantly shorter in the transcatheter group with a median of 2 [2.00-4.00] days compared to 8.5 [5.25-15.50] days in the surgical group (p < 0.001).
CONCLUSION: In our experience, percutaneous closure of patent ductus arteriosus is an efficient and safe alternative to surgery in 2 to 6 kg patients. Larger, multicentre studies are needed to confirm this statement.