Interstitial radiotherapy of malignant tumors of the vagina.

A total of 65 patients with malignant tumors of the vagina aged 32-81 years were treated by interstitial radiotherapy. Out of the 65 subjects, 52 patients were irradiated with 60Co sources, and 13 patients with 252Cf sources. Fixing devices of three types were used which ensured the practical realization of interstitial radiotherapy in regard to tumor localization, its shape, and volume. Complete tumor regression occurred in 54 patients (83.1%) and partial regression was observed in 9 patients (13.8%). Mild radiation reactions were found in 17 patients (26.1%). No effect was observed in 2 patients (3.1%). In one case necrotic radiation ulcer developed. On the basis of the above data the conclusion was drawn that interstitial radiotherapy represents the treatment of choice in malignant tumors of the vagina.