Journal of diabetes research · 2026
Risk Factors and Pregnancy Outcomes of Twin Pregnancies With Gestational Diabetes Mellitus: A Comparison Based on Chorionicity.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Huang Shuai, Li Xiaoyan, Zheng Jing, Qiu Gao, Luo Ping, Mao Lu, Qi Hongbo
Аннотация
BACKGROUND: There is insufficient evidence to determine whether the risk factors and pregnancy outcomes associated with gestational diabetes mellitus (GDM) in twin pregnancies vary by chorionicity.
MATERIALS: A retrospective cohort study was conducted among twin pregnancies. GDM was diagnosed using the IADPSG diagnostic criteria. Logistic regression and generalized estimation equation (GEE) models were used to identify the risk factors of GDM and its impact on pregnancy outcomes, stratified by monochorionic (MC) and dichorionic (DC) pregnancies.
RESULTS: Advanced maternal age (MC: aOR 2.18, 95% CI 1.25-3.81 and DC: aOR 1.32, 95% CI 1.06-1.67) and preexisting hypertension (MC: aOR 2.69, 95% CI 1.04-9.36 and DC: aOR 1.70, 95% CI 1.12-2.59) were risk factors for GDM regardless of chorionicity. Overweight (aOR 1.65, 95% CI 1.26-1.98), obesity (aOR 2.31, 95% CI 1.43-3.74), multiparity (aOR 1.43, 95% CI 1.10-1.88), assisted reproductive technology (ART) use (aOR 1.75, 95% CI 1.36-2.26), and polycystic ovary syndrome (PCOS) (aOR 1.98, 95% CI 1.37-4.12) were risk factors for GDM only in DC pregnancies. GDM was only associated with an increased risk of preeclampsia in MC pregnancies (aOR 1.29, 95% CI 1.04-2.26). GDM was associated with an increased risk of preterm delivery (PTD) at < 37 (aOR 1.13, 95% CI 1.05-1.34) and < 34 gestational weeks (aOR 1.15, 95% CI 1.07-1.75) in DC pregnancies.
CONCLUSION: The risk factors and pregnancy outcomes associated with GDM in twin pregnancies vary by chorionicity.
MATERIALS: A retrospective cohort study was conducted among twin pregnancies. GDM was diagnosed using the IADPSG diagnostic criteria. Logistic regression and generalized estimation equation (GEE) models were used to identify the risk factors of GDM and its impact on pregnancy outcomes, stratified by monochorionic (MC) and dichorionic (DC) pregnancies.
RESULTS: Advanced maternal age (MC: aOR 2.18, 95% CI 1.25-3.81 and DC: aOR 1.32, 95% CI 1.06-1.67) and preexisting hypertension (MC: aOR 2.69, 95% CI 1.04-9.36 and DC: aOR 1.70, 95% CI 1.12-2.59) were risk factors for GDM regardless of chorionicity. Overweight (aOR 1.65, 95% CI 1.26-1.98), obesity (aOR 2.31, 95% CI 1.43-3.74), multiparity (aOR 1.43, 95% CI 1.10-1.88), assisted reproductive technology (ART) use (aOR 1.75, 95% CI 1.36-2.26), and polycystic ovary syndrome (PCOS) (aOR 1.98, 95% CI 1.37-4.12) were risk factors for GDM only in DC pregnancies. GDM was only associated with an increased risk of preeclampsia in MC pregnancies (aOR 1.29, 95% CI 1.04-2.26). GDM was associated with an increased risk of preterm delivery (PTD) at < 37 (aOR 1.13, 95% CI 1.05-1.34) and < 34 gestational weeks (aOR 1.15, 95% CI 1.07-1.75) in DC pregnancies.
CONCLUSION: The risk factors and pregnancy outcomes associated with GDM in twin pregnancies vary by chorionicity.