Brain injury · 2003
Corpus callosum atrophy in adolescents with antecedents of moderate perinatal asphyxia.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Mañeru Cristina, Junqué Carme, Salgado-Pineda Pilar, Serra-Grabulosa Josep M, Bartrés-Faz David, Ramirez-Ruiz Blanca, Bargalló Núria, Tallada Mercè, Botet Francesc
Аннотация
BACKGROUND: The corpus callosum (CC) is a cerebral structure that reflects cognitive status in several neurological pathologies. Visual inspection of MRI has shown that hypoxic-ischemic encephalopathy(HIE) causes callosal damage.
PRIMARY OBJECTIVE: To quantify the CC surface in a sample of patients with antecedents of HIE and a group of matched controls.
RESEARCH DESIGN: Comparisons of CC measures among control subjects, mild HIE patients and moderateHIE patients as well as correlates of CC surface and neuropsychological performance.
METHODS: Twenty-one adolescent patients with childhood antecedents of HIE were compared to 21 controls. ANALYZE software was used to semi-automatically measure the CC area.
MAIN OUTCOMES AND RESULTS: Patients with moderate HIE showed corpus callosum reduction. The isthmus and genus were the most affected regions. Corpus callosum size correlated with cognitive function.
CONCLUSIONS: Corpus callosum quantification provides new evidence of subtle residual deficits in subjects with HIE antecedents without apparent neurological sequelae.
PRIMARY OBJECTIVE: To quantify the CC surface in a sample of patients with antecedents of HIE and a group of matched controls.
RESEARCH DESIGN: Comparisons of CC measures among control subjects, mild HIE patients and moderateHIE patients as well as correlates of CC surface and neuropsychological performance.
METHODS: Twenty-one adolescent patients with childhood antecedents of HIE were compared to 21 controls. ANALYZE software was used to semi-automatically measure the CC area.
MAIN OUTCOMES AND RESULTS: Patients with moderate HIE showed corpus callosum reduction. The isthmus and genus were the most affected regions. Corpus callosum size correlated with cognitive function.
CONCLUSIONS: Corpus callosum quantification provides new evidence of subtle residual deficits in subjects with HIE antecedents without apparent neurological sequelae.