The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2026
Hidden danger of microaxial flow pumps: Five cases of aortic and innominate mural thrombi.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
An Kevin R, Elmously Adham, Lee Junghun, Mitchell Drew, Fried Justin, Yunis Adil A, Masoumi Amirali, Yuzefpolskaya Melana, Colombo Paolo C, Sayer Gabriel T, Uriel Nir, Takeda Koji
Аннотация
Surgically implanted microaxial flow pumps (Impella 5.5, Abiomed, Danvers, MA) are increasingly used as a bridge to heart transplantation (BTT) or bridge to durable left ventricular assist device (LVAD) implantation, yet thrombotic complications remain incompletely characterized. We report 5 cases of aortic or innominate mural thrombi during Impella 5.5 support. Among 90 patients supported with Impella 5.5 as a BTT or bridge to LVAD between 2021 and 2025, 5 (5.5%) developed mural thrombi. Four patients underwent successful transplantation or LVAD implantation following thrombectomy or conservative management, while 1 patient experienced a fatal embolic stroke. These findings highlight an under-recognized mechanism of embolic stroke in patients supported with Impella 5.5 as a BTT or bridge to LVAD, and raise important considerations regarding anticoagulation targets, device explant techniques, and management of embolic complications. Further investigation is warranted to establish prevention and treatment strategies for this growing challenge.