Zhonghua fu chan ke za zhi · 1999
[Detection of antineutrophil cytoplasmic autoantibodies in pregnancy induced hypertension and its clinical significance].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Zhao W, Chen L, Wang L
Аннотация
OBJECTIVE: To explore the level of antineutrophil cytoplasmic autoantibodies (ANCA) in patients with pregnancy induced hypertension (PIH) and its clinical significance.
METHOD: 37 cases with PIH and 39 non-PIH pregnancy were studied for ANCA by indirect immunflourscence.
RESULTS: ANCA positive rates were 33.3%, 88.9% and 86.4% in mild, moderate, severe PIH, respectively, and most of them were c-ANCA. The positive rate was only 13.2% in non-PIH control, significantly lower than those in PIH (P < 0.001).
CONCLUSION: ANCA may be one of the causes for endothelial cell damage and a predicting marker in PIH.
METHOD: 37 cases with PIH and 39 non-PIH pregnancy were studied for ANCA by indirect immunflourscence.
RESULTS: ANCA positive rates were 33.3%, 88.9% and 86.4% in mild, moderate, severe PIH, respectively, and most of them were c-ANCA. The positive rate was only 13.2% in non-PIH control, significantly lower than those in PIH (P < 0.001).
CONCLUSION: ANCA may be one of the causes for endothelial cell damage and a predicting marker in PIH.