BMC pregnancy and childbirth · 2026
The impact of salt consumption on preeclampsia and proteinuria in pregnancy: A 24-hour urine sodium study.
СтатьяНазвание и аннотация: Перевод в очереди
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Sucu Sadun, Dereli Murat Levent, Aksan Alperen, Sucu Serap Topkara, Filiz Ahmet Arif, Özkan Merve Ayas, Yılmaz Zehra Vural, Çelen Şevki
Аннотация
OBJECTIVE: The aim was to investigate the association between salt consumption and preeclampsia, as well as the effects of salt consumption on proteinuria, fetal-maternal Doppler parameters, and neonatal outcomes.
METHODS: This case-control study was conducted at a large tertiary referral hospital from December 2023 to December 2024. During this period, 139 pregnant women at ≥ 20 weeks of gestation with suspected hypertension were hospitalized for assessment. After exclusions, 27 eligible participants who developed preeclampsia during follow-up comprised the preeclampsia group, while the remaining 73, who had healthy pregnancies, served as the control group. The primary outcome measures were daily salt consumption and proteinuria; secondary outcome measures were Doppler parameters and neonatal outcomes. Causality was investigated.
RESULTS: There was no significant difference in daily salt consumption between the preeclampsia and control groups (p = 0.490). However, in the control group, participants with proteinuria consumed significantly more salt than those without proteinuria (p < 0.001). Participants with proteinuria delivered at an earlier gestational age. Among the control group, those who consumed > 3 g/day of salt had significantly higher rates of proteinuria than those who consumed < 2 g/day (p = 0.004). Positive correlations between salt consumption and both proteinuria and 24-hour urinary creatinine excretion were found in all participants, including when only participants with proteinuria in the control group were considered.
CONCLUSION: Preeclampsia is not directly related to salt consumption. However, excessive salt consumption increases the risk of proteinuria and may contribute to hypertensive pregnancy disorders.
METHODS: This case-control study was conducted at a large tertiary referral hospital from December 2023 to December 2024. During this period, 139 pregnant women at ≥ 20 weeks of gestation with suspected hypertension were hospitalized for assessment. After exclusions, 27 eligible participants who developed preeclampsia during follow-up comprised the preeclampsia group, while the remaining 73, who had healthy pregnancies, served as the control group. The primary outcome measures were daily salt consumption and proteinuria; secondary outcome measures were Doppler parameters and neonatal outcomes. Causality was investigated.
RESULTS: There was no significant difference in daily salt consumption between the preeclampsia and control groups (p = 0.490). However, in the control group, participants with proteinuria consumed significantly more salt than those without proteinuria (p < 0.001). Participants with proteinuria delivered at an earlier gestational age. Among the control group, those who consumed > 3 g/day of salt had significantly higher rates of proteinuria than those who consumed < 2 g/day (p = 0.004). Positive correlations between salt consumption and both proteinuria and 24-hour urinary creatinine excretion were found in all participants, including when only participants with proteinuria in the control group were considered.
CONCLUSION: Preeclampsia is not directly related to salt consumption. However, excessive salt consumption increases the risk of proteinuria and may contribute to hypertensive pregnancy disorders.