[Research progress of decellularized matrix in tissue engineered trachea transplantation].

OBJECTIVE

To summarize the recent research situation and progress of decellularized matrix in tissue engineered trachea transplantation and to forecast the possible perspects.

METHODS

Recent original articles about study and application for decellularized matrix in tissue engineered trachea were reviewed. The application and study of different decellularized matrices involved in animals or patients with tracheal lesions were elaborated.

RESULTS

Decellularized matrices researched and applied in tissue engineered trachea include jejunum, urinary bladder, aorta, and trachea.

CONCLUSION

Decellularized urinary bladder matrix and jejunal matrix appears to be efficacious method for the patch repair of partial circumferential tracheal defects. The application of decellularized aortic matrix may need more study, and decellularized tracheal matrix has a bright future in long tracheal defects.