Arquivos de neuro-psiquiatria · 2017
Discordant clinical outcomes of congenital Zika virus infection in twin pregnancies.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Linden Vanessa van der, Linden Hélio van der, Leal Mariana de Carvalho, Rolim Epitacio Leite, Linden Ana van der, Aragão Maria de Fátima Viana Vasco, Brainer-Lima Alessandra Mertens, Cruz Danielle Di Cavalcanti Sousa, Ventura Liana O, Florêncio Telma Lúcia Tabosa, Cordeiro Marli Tenório, Caudas Silvio da Silva, Ramos Regina Coeli
Аннотация
Congenital Zika syndrome is an emergent cause of a congenital infectious disorder, resulting in severe damage to the central nervous system and microcephaly. Despite advances in understanding the pathophysiology of the disease, we still do not know all the mechanisms enrolled in the vertical transmission of the virus. As has already been reported in other types of congenital infectious disorders in dizygotic twin pregnancies, it is possible that the virus affects only one of the fetuses. In this article, we report on two cases of twin pregnancies exposed to the Zika virus, but with only one of the fetuses affected with microcephaly and brain damage. This indicates the urgent need for more studies regarding the pathophysiology of viral infection and the mechanisms involved in the natural protection against the virus.