Journal of pharmacy & bioallied sciences · 2025
Labor Induction versus Expectant Management: Evaluating Maternal and Neonatal Outcomes in Low-Risk Nulliparous Women.
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Rao Divya Raghavendra, Abilashini G D, Gnanasekaran Vijayalakshmi
Аннотация
AIM: This study aimed to compare the maternal and neonatal outcomes of elective labor induction at 39 weeks with expectant management in low-risk nulliparous women.
MATERIALS AND METHODS: A randomized controlled trial was conducted at ACS Medical College and Hospital, Chennai, over 6 months. A total of 100 low-risk nulliparous women with singleton pregnancies between 38 weeks 0 days and 38 weeks 6 days of gestation were randomized into two groups: labor induction (n = 50) and expectant management (n = 50). Statistical analysis was performed using an independent t-test to compare two groups, with a significance level of P < 0.05.
RESULTS: The labor induction group had a shorter labor duration (7.5 ± 2.3 vs. 9.2 ± 2.7 h; P = 0.003). The mode of delivery was similar, with vaginal births at 72% versus 64% (P = 0.34) and cesarean rates at 28% versus 36% (P = 0.42). Maternal complications (postpartum hemorrhage, P = 0.21; infection, P = 0.69) and neonatal outcomes (Apgar scores, birth weight, NICU admissions) showed no significant differences.
CONCLUSION: Labor induction at 39 weeks in low-risk nulliparous women shortens labor duration without increasing cesarean delivery rates, maternal complications, or adverse neonatal outcomes. These findings support the safety of elective labor induction in this population.
MATERIALS AND METHODS: A randomized controlled trial was conducted at ACS Medical College and Hospital, Chennai, over 6 months. A total of 100 low-risk nulliparous women with singleton pregnancies between 38 weeks 0 days and 38 weeks 6 days of gestation were randomized into two groups: labor induction (n = 50) and expectant management (n = 50). Statistical analysis was performed using an independent t-test to compare two groups, with a significance level of P < 0.05.
RESULTS: The labor induction group had a shorter labor duration (7.5 ± 2.3 vs. 9.2 ± 2.7 h; P = 0.003). The mode of delivery was similar, with vaginal births at 72% versus 64% (P = 0.34) and cesarean rates at 28% versus 36% (P = 0.42). Maternal complications (postpartum hemorrhage, P = 0.21; infection, P = 0.69) and neonatal outcomes (Apgar scores, birth weight, NICU admissions) showed no significant differences.
CONCLUSION: Labor induction at 39 weeks in low-risk nulliparous women shortens labor duration without increasing cesarean delivery rates, maternal complications, or adverse neonatal outcomes. These findings support the safety of elective labor induction in this population.