Journal of perinatology : official journal of the California Perinatal Association · 2025
Duration of noninvasive respiratory support in preterm infants: Association with gestational age and risk factors for delayed weaning.
СтатьяНазвание и аннотация: Перевод в очереди
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Eguchi Shu, Takeda Tomohiro, Nakao Atsushi
Аннотация
OBJECTIVE: To analyze the association between gestational age (GA) and postmenstrual age (PMA) at successful noninvasive respiratory support (NRS) -which includes noninvasive ventilation with neurally adjusted ventilatory assist (NIV-NAVA), nasal continuous positive airway pressure (nCPAP), and high-flow nasal cannula (HFNC)- weaning and to identify the risk factors affecting PMA at successful NRS weaning.
STUDY DESIGN: This retrospective cohort study included 449 preterm infants born before 32 weeks' GA who were admitted to the neonatal intensive care unit between 2015 and 2023.
RESULTS: The median PMA at successful weaning was 36.0 weeks. PMA at successful weaning was negatively correlated with GA. Only a small number of infants with earlier GA achieved successful weaning before 36 weeks of PMA. Earlier GA, small for GA, bubbly/cystic appearance on X-rays, and bowel perforation with ileostomy were identified as risk factors for delayed weaning.
CONCLUSION: Clinical interventions should consider these risks to optimize weaning outcomes.
STUDY DESIGN: This retrospective cohort study included 449 preterm infants born before 32 weeks' GA who were admitted to the neonatal intensive care unit between 2015 and 2023.
RESULTS: The median PMA at successful weaning was 36.0 weeks. PMA at successful weaning was negatively correlated with GA. Only a small number of infants with earlier GA achieved successful weaning before 36 weeks of PMA. Earlier GA, small for GA, bubbly/cystic appearance on X-rays, and bowel perforation with ileostomy were identified as risk factors for delayed weaning.
CONCLUSION: Clinical interventions should consider these risks to optimize weaning outcomes.