Biomarkers in medicine · 2024
The role of systemic immune-inflammatory index in predicting contrast-induced nephropathy in non-ST-segment elevation myocardial infarction cases.
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Tezen Ozan, Hayıroğlu Mert İlker, Pay Levent, Yumurtaş Ahmet Çağdaş, Keskin Kıvanç, Çetin Tuğba, Dereli Şeyda, Kadığoğlu Hikmet, Yücedağ Furkan Fatih, Arter Ertan, Dayı Şennur Ünal
Аннотация
Aim: Systemic immune-inflammation index (SII) is obtained by multiplying the platelets by the ratio of neutrophils to lymphocytes. We aimed to examine the relationship between contrast induced nephropathy (CIN) development and SII in non-ST-segment elevation myocardial infarction (NSTEMI) patients.Methods: 1124 NSTEMI patients included and divided into two groups according to the development of CIN. The relationship between SII and CIN development was examined.Results: Among two groups, significant differences were observed in terms of age, chronic renal failure, presence of critical stenoses in the LAD, SII and C-reactive protein (CRP). It was calculated that a value of 709 and above for SII had a predictive power with 74% sensitivity and 74% specificity for CIN.Conclusion: SII has the potential to predict the development of CIN in NSTEMI patients.