Management of a Patient With Polypharmacy Toxicity (Calcium Channel Blocker, Angiotensin Converting Enzyme Inhibitor and Tricyclic Antidepressant) in Intensive Care Settings: A Case Report.

We are presenting the case of a 28-year-old female patient who presented with refractory shock secondary to overdose of tricyclic antidepressants, calcium channel blockers (CCBs) and angiotensin-converting enzyme inhibitors. After initial resuscitation, bicarbonate infusion for TCA toxicity was used; and CCB toxicity was managed with high-dose insulin euglycemia therapy (HIET) with simultaneous dextrose infusion and vasopressors in the intensive care unit.