[Clinico-echographic parallels in patients with pyelonephritis and exacerbated chronic kidney failure].

24 patients with chronic renal failure due to chronic pyelonephritis were studied prospectively. In 18 of them (51%) the deterioration of the renal function was caused by obstruction, urinary infection, dehydration, etc. In 13 patients with chronic renal failure in exacerbation there were clinical data for activation of the pyelonephritis which was followed up dynamically. The ultrasound examination revealed enlarged kidneys with unclearly outlined renal structures. The changes were reversible and the pattern resembled that of acute renal failure. With the disappearance of the echographic data for interstitial renal edema an improvement of the renal function was established. The serum creatinine fell from 697.4 to 347.6 mumol/l (p less than 0.025) and plasma osmolality tell from 327.8 to 287 mOsm/l. No such changes were found in other II patients with chronic pyelonephritis and chronic renal failure without exacerbation.