[The effect of nifedipine on the microcirculation in pregnancy-induced hypertension].

OBJECTIVES

To study the effects of nifedipine on the microcirculation in pregnancy-induced hypertension (PIH).

METHODS

We observed the microcirculation in nailfold of 30 normal pregnant women and 76 cases of PIH. 20 mg nifedipine was given and nailfold microcirculation was observed after 30 minutes.

RESULTS

Nifedipine increased the velocity of blood flow, reduced the aggregation of erythrocytes, and dilated capillaries. After the administration of nifedipine, the total score of the nailfold microcirculation decreased significantly in mild and moderate PIH (P < 0.05), but no marked difference was observed in severe PIH cases (P > 0.05).

CONCLUSION

The disorder of the microcirculation of PIH can be improved by nifedipine.