Journal of perinatology : official journal of the California Perinatal Association · 2026
Left ventricular diastolic dysfunction in preterm infants with bronchopulmonary dysplasia.
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Phad Nilkant, Woodford Ryan, de Waal Koert
Аннотация
INTRODUCTION: Echocardiographic algorithm based assessment of diastolic function during neonatal period could help in early identification of left ventricular diastolic dysfunction (LVDD) in infants with bronchopulmonary dysplasia (BPD).
AIM: To screen infants with BPD at 36 weeks postmenstrual age for LVDD.
METHODS: We used conventional Doppler and myocardial deformation parameters suggested in the latest American Society of Echocardiography algorithm to evaluate LV function. Tricuspid-regurgitation velocity, LV shape, LV eccentricity and pulmonary ejection pattern were used to diagnose pulmonary hypertension (PH). The algorithm was then followed using age appropriate cut-off values to identify and grade LVDD.
RESULTS: Scans of 71 control infants and 93 infants with BPD were analysed. We noted PH in 15% infants with BPD and 7% control infants. Grade 2 LVDD was seen in 5% infants with BPD compared to 1.4% control infants.
CONCLUSION: Rate of PH and grade 2 LVDD was significantly higher in infants with moderate to severe BPD.
AIM: To screen infants with BPD at 36 weeks postmenstrual age for LVDD.
METHODS: We used conventional Doppler and myocardial deformation parameters suggested in the latest American Society of Echocardiography algorithm to evaluate LV function. Tricuspid-regurgitation velocity, LV shape, LV eccentricity and pulmonary ejection pattern were used to diagnose pulmonary hypertension (PH). The algorithm was then followed using age appropriate cut-off values to identify and grade LVDD.
RESULTS: Scans of 71 control infants and 93 infants with BPD were analysed. We noted PH in 15% infants with BPD and 7% control infants. Grade 2 LVDD was seen in 5% infants with BPD compared to 1.4% control infants.
CONCLUSION: Rate of PH and grade 2 LVDD was significantly higher in infants with moderate to severe BPD.