Changes in ambulatory blood pressure monitoring during the first half of pregnancy to predict preeclampsia.

This historical cohort study assessed 253 high-risk pregnant women to determine whether early pregnancy blood pressure (BP) changes, measured via office BP (OBP) and ambulatory BP monitoring (ABPM), predict preeclampsia (PE) or adverse maternal-fetal outcomes. BP was measured twice during early pregnancy, and 8.3% developed PE, while 30.4% experienced adverse outcomes. Although BP declined significantly between evaluations, these changes were not associated with PE or complications. Adjusted logistic regression models confirmed the lack of predictive value. Findings suggest that early BP changes, whether measured by OBP or ABPM, do not independently predict PE or adverse outcomes in high-risk pregnancies.