The treatment of clinically fixed inguinal lymph node metastases from carcinoma of the penis by chemotherapy and surgery.

A 50-year-old patient with carcinoma of the penis was referred for therapy of clinically fixed and ulcerated right inguinal adenopathy and mobile left inguinal adenopathy. He was treated initially by weekly infusions of methotrexate and bleomycin which resulted in clinical mobility and a decrease in size of his right sided adenopathy and re-epitheliazation of the overlying ulcer. A right- and subsequently a left-sided inguinal lymphadenectomy were performed. The patient remained clear of disease at follow-up 44 months after therapy.