Journal of Taibah University Medical Sciences · 2017
Maternal methyltetrahydrofolate reductase gene mutation in patients with missed abortions.
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Rady Helmy A
Аннотация
BACKGROUND: Missed abortions are a common problem, often caused by thrombophilia in both recurring and non-recurring cases.
AIM: To determine whether the presence of a mutation in the methyltetrahydrofolate reductase (Mthfr) gene correlates with missed abortions.
PATIENTS AND METHODS: We selected two hundred patients for this study in two groups: the study group, which consisted of one hundred patients with a history of missed abortion; and the control group, which consisted of one hundred patients with no history of missed abortion.
RESULTS: Of the 200 patients, mutations in Mthfr were only found in forty-four patients-thirty-four from the study group and ten from the control group.
CONCLUSIONS: Mthfr gene mutation is a common cause of both recurring and non-recurring missed abortions.
AIM: To determine whether the presence of a mutation in the methyltetrahydrofolate reductase (Mthfr) gene correlates with missed abortions.
PATIENTS AND METHODS: We selected two hundred patients for this study in two groups: the study group, which consisted of one hundred patients with a history of missed abortion; and the control group, which consisted of one hundred patients with no history of missed abortion.
RESULTS: Of the 200 patients, mutations in Mthfr were only found in forty-four patients-thirty-four from the study group and ten from the control group.
CONCLUSIONS: Mthfr gene mutation is a common cause of both recurring and non-recurring missed abortions.