Gastrointestinal stromal tumor of small intestine and synchronous bilateral papillary renal cell carcinoma.

Association of gastrointestinal stromal tumors (GISTs) with other primary malignant neoplasms has previously been reported. In addition, coexistence of unilateral renal cell cancer and a GIST of the stomach has been documented in the literature. We report herein a unique case of a GIST of the small intestine and bilateral papillary renal cell carcinomas in a patient presenting with melena and dizziness. Literature shows that GIST arising from the small intestine is the most common location of GIST accompanied by a second primary neoplasm. However, a unique feature in our GIST patient is the presence of synchronous (bilateral) papillary renal cell carcinomas.