American journal of obstetrics and gynecology · 2005
The syndrome of amniotic fluid embolism: a potential contribution of bradykinin.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Robillard Josée, Gauvin France, Molinaro Giuseppe, Leduc Line, Adam Albert, Rivard Georges E
Аннотация
OBJECTIVE: Amniotic fluid embolism is a potentially fatal complication of pregnancy; although several hypotheses have been formulated, the pathophysiology of this condition is not well known. An exaggerated release of bradykinin, which is activated by products of the amniotic fluid that enter the maternal circulation, could explain the symptoms that are present in amniotic fluid embolism. The objective of this study was to assess whether bradykinin is involved in amniotic fluid embolism.
STUDY DESIGN: The plasma bradykinin-generating capacity was measured serially in a patient who experienced amniotic fluid embolism.
RESULTS: The plasma bradykinin-generating capacity was found to be very low at the time of the initial clinical manifestations, which were characterized by severe hypotension, cardiorespiratory arrest, and coagulopathy.
CONCLUSION: This study suggests a potential role for bradykinin release in the pathophysiology of amniotic fluid embolism.
STUDY DESIGN: The plasma bradykinin-generating capacity was measured serially in a patient who experienced amniotic fluid embolism.
RESULTS: The plasma bradykinin-generating capacity was found to be very low at the time of the initial clinical manifestations, which were characterized by severe hypotension, cardiorespiratory arrest, and coagulopathy.
CONCLUSION: This study suggests a potential role for bradykinin release in the pathophysiology of amniotic fluid embolism.