EPI-CKD Brazil: point-of-care screening for chronic kidney disease during World Kidney Day.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Calice-Silva Viviane, Abreu Patrícia, Pinheiros Maria Eliete, Lopes Ana Katarina Cerqueira Delgado, Petruccelli Karla Cristina, Marinho Ana Wanda Barreto, Moura Ana Flávia, Neves Felipe Costa, Oliveira Cláudia Maria Costa, Costa Silvana Daher, Ulisses Luiz Roberto Sousa, Ferraz Fábio Humberto Ribeiro Paes, Souza Ramiele Aparecida Cruz, Armani Rachel Gatti, Costa Ciro Bruno, Tavares Marcelo Garcia, Brito Dyego José Araújo, Carneiro Erika Cristina Ribeiro Lima, Gonzaga Filho Luiz, Paixão Jenaine Oliveira, Sanders-Pinheiro Helady, Pinto Luis Claudio Santos, Nunes Lucas Acatauassu, Alves Pablo Rodrigues Costa, Silva Amanda Maíra Damasceno, Santos Neto René Scalet, Greffin Suzana Ricardo, Vajgel Gisele, Andrade João Marcelo Medeiros, Nascimento Ginivaldo Victor Ribeiro, Marques Igor Denizarde Bacelar, Holanda Maria Izabel, Rocha Pedro Tulio Monteiro Castro Abreu, O Kalyanne Cabral de Paula, Torauato Lelyanne Rodrigues Pereira, Karohl Cristina, Andrade Juliana Alves Manhaes, Sousa Ariane Karen, Simão Denise Rodrigues, Tome Ana Carolina Nakamura, Ponce Daniela, Gorayeb-Polacchini Fernanda Salomão, Alves Maria Almerinda Vieira Fernandes Ribeiro, Lodi Rubens Escobar Pires, Montenegro Cinthia, Moura-Neto José A
Аннотация
METHODS: We conducted a multicenter cross-sectional study across 20 state chapters of the Brazilian Society of Nephrology, including individuals ≥ 18 years with at least one CKD risk factor (age > 60 years, hypertension [HTN], diabetes mellitus [DM], cardiovascular disease, obesity, chronic use of nonsteroidal anti-inflammatory drugs, history of acute kidney injury, bilateral kidney stones, or family history of CKD). Renal function was assessed using a rapid creatinine test (NovaMaxPro®-eGFR CKD-EPI 2021). Reduced eGFR was defined as < 60 mL/min/1.73 m2.
RESULTS: We analyzed 8,374 participants (66.9% women; median age, 58 years; BMI, 28.3 kg/m2; 46.2% mixed race). The frequency of reduced eGFR was 40.2% (n = 3,370), of whom 36% were in stages G3b-G5. Only 35.2% were aware of CKD risk factors. Significant regional differences were observed (ranging from 27.9% [Bahia] to 55.2% [Paraná]; p < 0.001). Independent predictors included age (OR = 1.032; 95%CI: 1.028-1.035), HTN (OR = 1.27; 95%CI: 1.15-1.40), and indigenous ethnicity as a protective factor (OR = 0.40; 95%CI: 0.20-0.89; p < 0.05). Risk increased by 23% for each additional risk factor.
CONCLUSION: A high frequency of reduced eGFR and low awareness of CKD risk factors were observed. The study demonstrates the feasibility of POCTcr in screening strategies and reinforces the need for public policies to expand early diagnosis and strengthen primary care.