Pediatric nephrology (Berlin, Germany) · 2024
Poststreptococcal acute glomerulonephritis with 22F pneumococcal bacteremia.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
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Itagaki Hinako, Watanabe Yoshitaka, Yagi Naomi, Iwaku Takashi, Kawai Nobuhiro, Ikeda Hirokazu
Аннотация
BACKGROUND: Pneumococcal vaccines have been available worldwide since the early 2000s; consequently, few reports exist of poststreptococcal acute glomerulonephritis (PSAGN) or complications of pneumococcal infection. We describe a patient with PSAGN and bacteremia with Streptococcus pneumoniae serotype 22F (not covered by the 13-valent pneumococcal vaccine (PCV 13)).
CASE DIAGNOSIS/TREATMENT: A 5-year-old boy received the PCV13 vaccine and was admitted to our hospital with a fever and gross hematuria. A throat swab was positive for a streptococcal antigen, and his serum anti-streptolysin O and creatinine levels were increased. Low serum C3 levels suggested PSAGN, with an infiltrating shadow on chest X-ray. His blood culture isolated S. pneumoniae serotype 22F, and he was administered intravenous ceftriaxone for 10 days. His kidney function, pneumonia, and bacteremia improved.
CONCLUSIONS: Children with PSAGN should be evaluated for pneumococcal bacteremia due to strains not covered by the vaccine.
CASE DIAGNOSIS/TREATMENT: A 5-year-old boy received the PCV13 vaccine and was admitted to our hospital with a fever and gross hematuria. A throat swab was positive for a streptococcal antigen, and his serum anti-streptolysin O and creatinine levels were increased. Low serum C3 levels suggested PSAGN, with an infiltrating shadow on chest X-ray. His blood culture isolated S. pneumoniae serotype 22F, and he was administered intravenous ceftriaxone for 10 days. His kidney function, pneumonia, and bacteremia improved.
CONCLUSIONS: Children with PSAGN should be evaluated for pneumococcal bacteremia due to strains not covered by the vaccine.