Intraoperative Intramedullary Photobiomodulation Therapy for Consolidation of Atypical Femoral Fractures in Elderly Women: A Pilot Study.

BACKGROUND

Atypical femoral fractures (AFFs) are rare complications often linked to prolonged bisphosphonate use. This pilot study evaluated the feasibility of intraoperative intramedullary photobiomodulation therapy (PBMT) using long, sterile optical fibers during surgical fixation.

METHODS

Eleven elderly female patients with AFFs were randomized into a PBMT-treated group or control. PBMT was applied using a red laser (638 nm, 3.2 J per point).

RESULTS

No statistically significant differences in healing, complications, or function were observed. However, a trend toward improved RUSTm scores in the PBMT group emerged.

CONCLUSION

This novel technique appears feasible and safe; further studies are needed to assess its regenerative potential.