Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association · 2012
Wound dehiscence and stump infection after lower limb amputation: risk factors and association with antibiotic use.
СтатьяНазвание и аннотация: Перевод в очереди
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Dunkel Nathalie, Belaieff Wilson, Assal Mathieu, Corni Valentina, Karaca Şaziye, Lacraz Alain, Uçkay Ilker
Аннотация
BACKGROUND: Optimal duration of antibiotic prophylaxis following major lower limb amputation in preventing adverse stump outcomes is controversial.
OBJECTIVE: We assess the epidemiology and risk factors of wound dehiscence and stump infection after mid-thigh to transmetatarsal amputations with regard to antibiotic administration.
METHODS: Our retrospective observational study at the Geneva University Hospital (January 1995-June 2010) includes a total of 289 amputations in 270 adult patients (199 males; median age 70 years).
RESULTS: Wound dehiscence and/or stump infection occurred in 47 (16.3%) and 63 (21.8%) patients with a median delay of 24 and 14 days, respectively. No clinical variable was significantly associated with stump infection. Diabetes and older age (>80 years) were associated with dehiscence. Importantly, transcutaneous tissue oxygen tension (TcPO2) and duration of antibiotic administration showed no association with either outcome.
CONCLUSION: The duration of antibiotic administration before or after surgery does not change the epidemiology of stump complications.
OBJECTIVE: We assess the epidemiology and risk factors of wound dehiscence and stump infection after mid-thigh to transmetatarsal amputations with regard to antibiotic administration.
METHODS: Our retrospective observational study at the Geneva University Hospital (January 1995-June 2010) includes a total of 289 amputations in 270 adult patients (199 males; median age 70 years).
RESULTS: Wound dehiscence and/or stump infection occurred in 47 (16.3%) and 63 (21.8%) patients with a median delay of 24 and 14 days, respectively. No clinical variable was significantly associated with stump infection. Diabetes and older age (>80 years) were associated with dehiscence. Importantly, transcutaneous tissue oxygen tension (TcPO2) and duration of antibiotic administration showed no association with either outcome.
CONCLUSION: The duration of antibiotic administration before or after surgery does not change the epidemiology of stump complications.