[Preliminary clinical experience of domestic robot-assisted laparoscopic radical nephrectomy with venous tumor thrombectomy].

OBJECTIVE

To preliminarily investigate the safety and feasibility of domestic Jingfeng MP1000 multi-port robotic surgical system-assisted laparoscopic radical nephrectomy with venous tumor thrombectomy.

METHODS

Clinical data of 15 patients with renal cell carcinoma (RCC) and venous tumor thrombus who underwent Jingfeng MP1000 robot-assisted laparoscopic radical nephrectomy with venous tumor thrombectomy at the Department of Urology, Peking University Third Hospital from June 2024 to January 2026 were retrospectively analyzed. The primary outcomes were the success rate of the robotic procedure, overall complication rate, and major complication rate (Clavien-Dindo ≥ grade Ⅲ). Secondary outcomes included operative time, estimated blood loss, and length of hospital stay. Baseline characteristics, perioperative outcomes, pathological results, and postoperative complications were collected and analyzed using descriptive statistical methods.

RESULTS

All the 15 procedures were successfully completed with robotic assistance, with no conversions to open surgery. The success rate of robotic-assisted surgery was 100%. The median patient age was 60 years, and the median body mass index was 25.6 kg/m2. Ten patients had right-sided and 5 had left-sided tumors, with a median tumor diameter of 9.1 cm. According to the Mayo classification, there were 5 cases of grade 0, 4 of grade Ⅰ, 5 of grade Ⅱ, and 1 of grade Ⅲ thrombus. The median operative time was 233.0 min, the median estimated blood loss was 250.0 mL, and 5 patients (33.3%) received blood transfusions. The median postoperative hospital stay was 6 days. Only one patient (6.7%) experienced a Clavien-Dindo grade Ⅱ complication (lymphatic leakage), with no grade ≥Ⅲ severe complications or perioperative mortality. Postoperative pathology revealed clear cell renal cell carcinoma in 12 cases, and venous wall invasion was confirmed in 8 patients (53.3%). After a median follow-up of 4.4 months, one patient developed duodenal metastasis 10 months postoperatively.

CONCLUSION

The domestic Jingfeng MP1000 multi-port robotic system-assisted laparoscopic radical nephrectomy with venous tumor thrombectomy is technically safe and feasible, with favorable perioperative outcomes and a low complication rate. Its long-term oncological efficacy requires further validation through large-scale, prospective studies.