Archives of physical medicine and rehabilitation · 2008
Intradermal botulinum toxin type A injection effectively reduces residual limb hyperhidrosis in amputees: a case series.
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Charrow Alexandra, DiFazio Marc, Foster Leslie, Pasquina Paul F, Tsao Jack W
Аннотация
OBJECTIVE: To study the effectiveness of botulinum toxin type A (BTX-A) therapy for residual limb hyperhidrosis, prosthesis fit and function, and residual and phantom limb pain in patients with limb amputation.
DESIGN: Consecutive case series.
SETTING: Outpatient physical medicine and rehabilitation clinic.
PARTICIPANTS: Walter Reed Army Medical Center patients (N=8) with unilateral traumatic upper- or lower-limb amputation.
INTERVENTION: BTX-A was injected transdermally in a circumferential pattern around the residual limb by using a 1-cm matrix grid.
MAIN OUTCOME MEASURE: A 10-cm continuous Likert visual analog scale was used to assess residual limb sweating and pain and prosthesis fit and function before and 3 weeks after BTX-A injections.
RESULTS: Patients reported a significant reduction in sweating and improvement in prosthesis fit and function after treatment. However, residual limb and phantom pain were unaffected by treatment.
CONCLUSIONS: BTX-A may be an effective treatment for residual limb hyperhidrosis, resulting in subjective improvement in prosthesis fit and functioning. BTX-A should be considered as a method to manage excessive sweating in the residual limb of traumatic amputees.
DESIGN: Consecutive case series.
SETTING: Outpatient physical medicine and rehabilitation clinic.
PARTICIPANTS: Walter Reed Army Medical Center patients (N=8) with unilateral traumatic upper- or lower-limb amputation.
INTERVENTION: BTX-A was injected transdermally in a circumferential pattern around the residual limb by using a 1-cm matrix grid.
MAIN OUTCOME MEASURE: A 10-cm continuous Likert visual analog scale was used to assess residual limb sweating and pain and prosthesis fit and function before and 3 weeks after BTX-A injections.
RESULTS: Patients reported a significant reduction in sweating and improvement in prosthesis fit and function after treatment. However, residual limb and phantom pain were unaffected by treatment.
CONCLUSIONS: BTX-A may be an effective treatment for residual limb hyperhidrosis, resulting in subjective improvement in prosthesis fit and functioning. BTX-A should be considered as a method to manage excessive sweating in the residual limb of traumatic amputees.