The profile of the resistance of Staphylococcus aureus against selected antibiotics in Najaf.

OBJECTIVE

Aim: In this study, we examine and discuss about the resistance of Staphylococcus aureus to common antibiotic classes in Najaf.

PATIENTS AND

METHODS

Materials and methods: Information on Staphylococcus aureus's resistance to drugs was collected from the directorate of health and analyzed.

RESULTS

Results

It was found that Staphylococcus aureus exhibited resistance to cephalosporins that was comparable to that of penicillin. On the other hand, significant resistance to cefoxitine, ceftazidim, and penicillin was seen, further studies are required to evaluate the mechanism of antibiotic resistance responsible for such resistance.

CONCLUSION

Conclusions

the profile of resistance of Staphylococcus aureus is variable across antibiotic families. Inter-member differences have been noticed within the group, a pattern that more likely indicates resistance at the level of intracellular concentration of antibiotic rather than the mechanism of action. In addition, it has been noticed that the development of resistance is directly proportional to the frequency of use of antibiotics. Further studies are required to investigate the molecular mechanism of resistance.