Fertility and sterility · 2009
Monozygotic multiple gestation after intracytoplasmic sperm injection and preimplantation genetic diagnosis.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Haimov-Kochman Ronit, Daum Hagit, Lossos Francine, Aizenman Einat, Werner Marion, Yagel Simcha, Laufer Neri, Simon Alex, Hurwitz Arye
Аннотация
OBJECTIVE: To report a possible association between intracytoplasmic sperm injection (ICSI)-preimplantation genetic diagnosis (PGD) and monozygotic multiple gestation.
DESIGN: Small case series.
SETTING: In vitro fertilization unit in an academic medical center.
PATIENT(S): Three patients were treated with ICSI-PGD for sexing as well as selection against a known translocation.
INTERVENTION(S): Transfer of day 4 embryos to the uterus.
MAIN OUTCOME MEASURE(S): Clinical pregnancy.
RESULT(S): Two pairs of monozygotic twins and a triplet pregnancy.
CONCLUSION(S): Repeated manipulation of the zona pellucida as well as extended embryo culture during ICSI-PGD treatments may result in monozygotic twin and triplet pregnancies.
DESIGN: Small case series.
SETTING: In vitro fertilization unit in an academic medical center.
PATIENT(S): Three patients were treated with ICSI-PGD for sexing as well as selection against a known translocation.
INTERVENTION(S): Transfer of day 4 embryos to the uterus.
MAIN OUTCOME MEASURE(S): Clinical pregnancy.
RESULT(S): Two pairs of monozygotic twins and a triplet pregnancy.
CONCLUSION(S): Repeated manipulation of the zona pellucida as well as extended embryo culture during ICSI-PGD treatments may result in monozygotic twin and triplet pregnancies.