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Войти в исследования Journal of gynecology obstetrics and human reproduction · 2026
Associations of air pollution exposure with anti-Müllerian hormone as an ovarian reserve biomarker: A systematic review.
СтатьяСистематический обзорНазвание и аннотация: Перевод в очереди
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Mandalou Leila, Aghebati-Maleki Ali, Mardi Amirhossein, Yousefi Mehdi, Aghebati-Maleki Leili
Аннотация
BACKGROUND: Reproductive health is essential to women's well-being. Rising infertility rates are influenced by environmental and lifestyle factors. Aging significantly reduces ovarian reserve and oocyte quality, especially after age 35. Anti-Müllerian hormone (AMH) is a reliable marker for assessing ovarian reserve. Air pollution, particularly exposure to particulate matter (PM) and nitrogen oxides (NOx), may be negatively associated with ovarian reserve and reproductive health.
OBJECTIVES: To evaluate current evidence on the effects of air pollution on AMH levels.
METHODS: We systematically searched PubMed, Embase, and Web of Science for studies published from January 2000 until December 29, 2024, using specific keywords. Two reviewers independently screened studies based on predefined inclusion criteria, focusing on original articles examining the relationship between air pollutants and AMH levels. Data were extracted using Google Sheets. Study quality was assessed using the AXIS tool for cross-sectional studies and the Newcastle-Ottawa Scale for cohort studies.
RESULTS: Twelve studies were included. Nine reported a significant association between air pollution and reduced AMH levels. The methodological quality of studies ranged from fair to good, supporting the robustness of findings.
CONCLUSION: Air pollution may significantly reduce ovarian reserve. Reducing exposure to PM2.5 and NOx is crucial for fertility preservation, especially in polluted urban areas.
OBJECTIVES: To evaluate current evidence on the effects of air pollution on AMH levels.
METHODS: We systematically searched PubMed, Embase, and Web of Science for studies published from January 2000 until December 29, 2024, using specific keywords. Two reviewers independently screened studies based on predefined inclusion criteria, focusing on original articles examining the relationship between air pollutants and AMH levels. Data were extracted using Google Sheets. Study quality was assessed using the AXIS tool for cross-sectional studies and the Newcastle-Ottawa Scale for cohort studies.
RESULTS: Twelve studies were included. Nine reported a significant association between air pollution and reduced AMH levels. The methodological quality of studies ranged from fair to good, supporting the robustness of findings.
CONCLUSION: Air pollution may significantly reduce ovarian reserve. Reducing exposure to PM2.5 and NOx is crucial for fertility preservation, especially in polluted urban areas.