Corneal perforation with secondary congenital aphakia in Peters anomaly.

PURPOSE: To describe two cases of secondary congenital aphakia in association with Peters anomaly.

METHODS

Two infants were noted to have corneal opacification at birth. Each child was found to have Peters anomaly requiring corneal transplantation in 1 or both eyes.

RESULTS

Each child underwent penetrating keratoplasty, revealing absence of the crystalline lens in 1 eye. Histopathologic evaluation of the corneal buttons was performed. Each specimen showed full-thickness corneal defects with lens remnants.

CONCLUSIONS

Secondary congenital aphakia from corneal perforation should be considered in the presentation of severe Peters anomaly.